[1]李毅斌,曹漫明,胡喜钢,等.射频消融术联合肝动脉化疗栓塞及西妥昔单抗治疗结直肠癌肝转移的疗效评价[J].介入放射学杂志,2016,(02):129-133.
 LI Yi- bin,CAO Man- ming,HU Xi- gang,et al. Evaluation of radiofrequency ablation combined with transcatheter arterial chemoembolization and cetuximab in treating hepatic metastases from colorectal cancer[J].journal interventional radiology,2016,(02):129-133.
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射频消融术联合肝动脉化疗栓塞及西妥昔单抗治疗结直肠癌肝转移的疗效评价 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2016年02期
页码:
129-133
栏目:
肿瘤介入
出版日期:
2016-02-25

文章信息/Info

Title:
 Evaluation of radiofrequency ablation combined with transcatheter arterial chemoembolization and cetuximab in treating hepatic metastases from colorectal cancer
作者:
李毅斌 曹漫明 胡喜钢 范子荣 汪森明
Author(s):
LI Yi- bin CAO Man- ming HU Xi- gang FAN Zi- rong WANG Sen- ming
Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong Province 510282, China
关键词:
【关键词】 结直肠癌肝转移 射频消融 肝动脉栓塞化疗 西妥昔单抗
文献标志码:
A
摘要:
【摘要】 目的 探究射频消融术(RFA)联合肝动脉栓塞化疗术(TACE)及西妥昔单抗(cetuximab)治疗结直肠癌肝转移的临床疗效。方法 回顾性分析2010年1月—2014 年1月49例结直肠癌肝转移患者,分为治疗组(RFA+TACE+cetuximab)23例和对照组(TACE+cetuximab)26例,观察两组患者治疗后实体瘤疗效、1年总生存率(OS)、1年无进展生存率(PFS)及不良反应的情况。结果 治疗组的完全缓解率达到73.9%(17/23),明显优于对照组的26.9%(7/26),差异有统计学意义(P<0.05)。治疗组及对照组的OS差异无统计学意义(P>0.05);但治疗组的 1年PFS为52.2%,优于对照组的23.1%,差异有统计学意义(P<0.05)。结论 对于无法手术的结直肠癌肝转移患者,RFA联合TACE及西妥昔单抗治疗的近期疗效及1年PFS优于单纯TACE联合西妥昔单抗治疗,具有肿瘤完全坏死率高、肝内复发率低的优点。

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2015-07-20)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2016-02-22