[1]梅百强,杨希立,许兆延,等.H型高血压患者斑块特征与同型半胱氨酸相关性研究 [J].介入放射学杂志,2016,(01):70-73.
 MEI Bai- qiang,YANG Xi- li,XU Zhao- yan,et al.Study on the relationship between plaque imaging characteristics and homocysteine in patients with H- type hypertension [J].journal interventional radiology,2016,(01):70-73.
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H型高血压患者斑块特征与同型半胱氨酸相关性研究

 

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2016年01期
页码:
70-73
栏目:
临床研究
出版日期:
2016-01-25

文章信息/Info

Title:
Study on the relationship between plaque imaging characteristics and homocysteine in patients with H- type hypertension 
作者:
梅百强 杨希立 许兆延 梁 茜 岑锦明 周昭仑 李健民李 健 蔡炜标
Author(s):
MEI Bai- qiang YANG Xi- li XU Zhao- yan LIANG Qian CEN Jin- ming ZHOU Zhao- lun LI Jian- min LI Jian CAI Wei- biao
Department of Cardiology, Affiliated Foshan Municipal First People’s Hospital, Zhongshan University, Foshan, Guangdong Province 528000, China
关键词:
【关键词】 H型高血压 同型半胱氨酸 冠状动脉造影术 血管内超声 动脉粥样硬化
文献标志码:
A
摘要:
【摘要】 目的 对冠状动脉造影显示轻中度狭窄病变作血管内超声(IVUS)检查,分析H型高血压患者冠状动脉粥样硬化斑块形态特征,探讨同型半胱氨酸(Hcy)水平与病变程度的关系及临床意义。 方法 回顾性分析H型高血压患者42例和单纯高血压患者38例。所有患者均接受血浆Hcy水平检测,IVUS分别检测冠状动脉病变段和正常参考段外弹力膜横截面积(EEMCSA)、最小管腔横截面积(MLA)、斑块面积(PA)、斑块负荷(PB)等,并作定性指标和定量指标分析。结果 H型高血压组患者冠状动脉病变处软斑块、偏心斑块和正性重构多见,钙化少;单纯高血压组患者斑块多表现为纤维斑块、钙化、无重构和负性重构(P<0.05)。H型高血压组患者病变段MLA<单纯高血压组患者,EEMCSA、PA、PB>单纯高血压组患者(P<0.05);H型高血压组患者正常参考段MLA<单纯高血压组患者,RPA、RPB>单纯高血压组患者(P<0.05)。病变段Hcy水平与病变段PA、PB呈正相关(P<0.05),与病变段MLA呈负相关(P<0.05)。结论 IVUS对评价轻中度病变有较高价值,H型高血压患者冠状动脉病变程度较单纯高血压患者严重和弥漫。Hcy水平对判断冠状动脉病变程度有一定价值,高Hcy水平可能是导致斑块不稳定的因素之一。


参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2015-05-05)
(本文编辑:边 佶)
更新日期/Last Update: 2016-01-22