[1]严 昆,陈敏华,李荣杰,等. 残留复发性肝肿瘤射频消融治疗——超声造影的应用价值[J].介入放射学杂志,2014,(06):496-499.
 YAN Kun,CHEN Min- hua,LEE Jung- chieh,et al. The clinical application of contrast enhanced ultrasonography in radiofrequency ablation therapy for residual and recurrent hepatic neoplasms[J].journal interventional radiology,2014,(06):496-499.
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 残留复发性肝肿瘤射频消融治疗——超声造影的应用价值()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年06期
页码:
496-499
栏目:
非血管介入
出版日期:
2014-07-05

文章信息/Info

Title:
 The clinical application of contrast enhanced ultrasonography in radiofrequency ablation therapy for residual and recurrent hepatic neoplasms
作者:
 严 昆 陈敏华 李荣杰 吴 薇 张仲一 王延杰 杨 薇
Author(s):
 YAN Kun CHEN Min- hua LEE Jung- chieh WU Wei ZHANG Zhong- yi WANG Yan- jie YANG Wei.
 Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing 100142, China
关键词:
 【关键词】 超声检查 造影剂 肝肿瘤 射频消融术
文献标志码:
A
摘要:
 【摘要】 目的 探讨对比增强超声(CEUS)在肝脏残留复发性恶性肿瘤进行射频消融(RFA)治疗的临床应用。方法 517例原发性肝癌(HCC)、肝转移癌患者经各种治疗后残留或局部复发拟行RFA治疗,共619个病灶为研究对象。复发HCC 281例290灶,病灶大小平均(3.4 ± 1.5)cm,其中CEUS引导治疗组150例154灶,常规超声引导组131例136灶。另复发肝转移癌236 例329 灶,病灶大小平均(3.1 ± 1.3)cm,其中CEUS引导治疗组152例198 灶,常规超声引导组84例131灶。结果 复发HCC CEUS组与常规组治疗结果比较:1个月肿瘤灭活率分别为96.1%和89.7%(P = 0.032);肿瘤局部复发率各为9.7%和17.6%(P = 0.049);两组间差异均有统计学意义。复发肝转移癌CEUS组与常规组治疗结果比较:1个月肿瘤灭活率88.4%和87.0%(P = 0.712);肿瘤局部复发率16.7%和23.7%(P = 0.117),两组间差异均无统计学意义。结论 CEUS 指导RFA治疗复发HCC,可有效提高早期灭活率,降低局部复发。

参考文献/References:

 [1] 葛勇胜, 许戈良, 李建生, 等. 增强CT和超声造影检查在肝癌射频消融中的应用价值[J]. 肿瘤, 2012, 32: 462 - 465.
[2] 丁 红, 王文平, 魏瑞雪, 等. 实时灰阶超声造影和螺旋CT诊断肝肿瘤的比较研究[J]. 中国医学影像技术, 2004, 20: 728 - 730.
[3] 严 昆, 陈敏华, 杨 薇, 等. 超声造影评价肝恶性肿瘤射频治疗疗效—与常规超声及增强CT比较[J]. 中华超声影像学杂志, 2005, 14: 655 - 658.
[4] Chen MH, Yang W, Yan K, et al. Large liver tumors: protocol for radiofrequency ablation and its clinical application in 110 patients—mathematic model, overlapping mode, and electrode placement process[J]. Radiology, 2004, 232: 260 - 271.
[5] Dai Y, Chen MH, Yin SS, et al. Focal liver lesions: can SonoVue- enhanced ultrasound be used to differentiate malignant from benign lesions?[J]. Invest Radiol, 2007, 42: 596 - 603.
[6] Frieser M, Kiesel J, Lindner A, et al. Efficacy of contrast- enhanced US versus CT or MRI for the therapeutic control of percutaneous radiofrequency ablation in the case of hepatic malignancies[J]. Ultraschall Med, 2011, 32: 148 - 153.
[7] Wu J, Yang W, Yin S, et al. Role of contrast- enhanced ultrasonography in percutaneous radiofrequency ablation of liver metastases and efficacy evaluation[J]. Chin J Cancer Res, 2013, 25: 143 - 154.
[8] 曾燕荣, 陈敏华, 严 昆, 等. 超声造影界定肝癌浸润范围的应用价值[J]. 中华医学杂志, 2006, 86: 3294 - 3298.
[9] Nakazawa T, Kokubu S, Shibuya A, et al. Radiofrequency ablation of hepatocellular carcinoma: correlation between local tumor progression after ablation and ablative margin[J]. AJR, 2007, 188: 480 - 488.
[10] Rennert J, Georgieva M, Schreyer AG, et al. Image fusion of contrast enhanced ultrasound (CEUS) with computed tomography (CT) or magnetic resonance imaging(MRI) using volume navigation for detection, characterization and planning of therapeutic interventions of liver tumors[J]. Ultraschall Med, 2011, 49: 67 - 81.
[11] 李 凯, 许尔蛟, 郑荣琴, 等. 融合成像超声造影术中即时评估肝癌射频消融疗效[J]. 中华超声影像学杂志, 2013, 22: 587 - 590.
[12] Koh YH, Choi JI, Kim HB, et al. Computed tomographic- guided radiofrequency ablation of recurrent or residual hepatocellular carcinomas around retained iodized oil after transarterial chemoembolization[J]. Korean J Radiol, 2013, 14: 733 - 742.

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备注/Memo

备注/Memo:
 (收稿日期:2014-02-17)
更新日期/Last Update: