[1]程景林,万 俊,王爱玲.介入诊疗对心血管病患者外周淋巴细胞DNA的损伤[J].介入放射学杂志,2012,(07):551-553.
 CHENG Jing? lin,WAN Jun,WANG Ai- ling.. Acute chromosomal DNA damage of human lymphocytes caused by radiation exposure produced in performing interventional cardiovascular procedures[J].journal interventional radiology,2012,(07):551-553.
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介入诊疗对心血管病患者外周淋巴细胞DNA的损伤 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2012年07期
页码:
551-553
栏目:
血管介入
出版日期:
2012-07-30

文章信息/Info

Title:
 Acute chromosomal DNA damage of human lymphocytes caused by radiation exposure produced in performing interventional cardiovascular procedures
作者:
 程景林 万 俊 王爱玲
Author(s):
 CHENG Jing?蛳 lin WAN Jun WANG Ai- ling.
 Department of Emergency Internal Medicine, the Second Affiliated Hospital, Anhui Medical University, Hefei 230601, China
关键词:
 【关键词】 心血管疾病 介入治疗 DNA损伤 电离辐射
文献标志码:
A
摘要:
 【摘要】 目的 探讨心血管病介入诊疗中的X线电离辐射对心血管病患者DNA损伤的影响。方法 收治接受心血管病介入诊疗患者244例,按介入术式不同分为四组:经皮冠状动脉造影术组87例,经皮冠状动脉介入术组72例,射频消融术组48例,起搏器植入术组37例。分别于术前、术后2 h、 24 h抽取患者外周血,检测外周血淋巴细胞染色体微核。同时记录患者手术全程辐射的累积皮肤表面入射剂量(CD)、面积剂量乘积(DAP)、透视时间(FT)等,观察各种介入诊疗中患者接受的辐射损伤程度和差异。结果 经皮冠状动脉支架置入术组CD和DAP值显著高于其他三组,而其他三组间CD和DAP值差异无统计学意义(P > 0.05)。患者术后2 h染色体微核率为16.3‰ ± 4.2‰,P < 0.05),术后24 h为17.5‰ ± 5.1‰,,明显高于术前水平(13.8‰ ± 4.7‰,P < 0.05)。结论 不同介入术中,患者接受的辐射剂量不同,但介入诊疗中的电离辐射都可能会造成患者的DNA损伤。

参考文献/References:

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备注/Memo

备注/Memo:
 (收稿日期:2012-01-05)
更新日期/Last Update: