[1]汪建华,左长京,邵成伟,等. CT引导下125Ⅰ粒子植入治疗腹部淋巴结转移癌的 临床应用[J].介入放射学杂志,2011,(11):877-881.
 WANG Jian-hua,ZUO Chang-jing,SHAO Cheng-wei,et al.CT-guided 125Ⅰ seed brachytherapy for abdominal metastatic lymph nodes[J].journal interventional radiology,2011,(11):877-881.
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 CT引导下125Ⅰ粒子植入治疗腹部淋巴结转移癌的 临床应用 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2011年11期
页码:
877-881
栏目:
非血管介入
出版日期:
2011-11-25

文章信息/Info

Title:
CT-guided 125Ⅰ seed brachytherapy for abdominal metastatic lymph nodes
作者:
 汪建华 左长京 邵成伟 马小龙 张 建 田建明
200433  上海 第二军医大学附属长海医院放射科,核医学科;浙江省宁波市第二医院放射科
Author(s):
WANG Jian-hua ZUO Chang-jing SHAO Cheng-wei MA Xiao-long Zhang Jian TIAN Jian-ming.
Department of Radiology, the Affiliated Changhai Hospital, Second Military Medical University, Shanghai 200433, China
关键词:
【关键词】 肿瘤 肿瘤转移 淋巴结 腹部 体层摄影术 X线计算机 近距离放射疗法 碘放射性核素
分类号:
R733.4
文献标志码:
A
摘要:
 【摘要】   目的 探讨CT引导下125Ⅰ粒子植入术治疗腹部恶性肿瘤的腹腔及腹膜后区转移性淋巴结的安全性及疗效。方法 回顾性分析27例经病理确诊的腹部恶性肿瘤患者共31枚腹腔及腹膜后区转移性淋巴结(直径2.2 ~ 4.7 cm)接受经CT引导下125Ⅰ放射性粒子植入治疗的临床资料。植入量遵循Halarism 125Ⅰ经验公式确定,粒子活度为0.5 ~ 0.85 mCi,以间距1.0 ~ 1.5 cm布源。植入完毕后即行CT扫描,了解粒子分布情况及有无并发症。植入术后3个月行CT或PETCT复查,参考WHO实体肿瘤评价标准进行影像学疗效评估。结果 27例中,25例手术一次植入成功,达到剂量要求,粒子分布满意率92.6%(25/27例),2例首次术后未达到要求而补种粒子。术前8例伴有明显疼痛患者中,6例于术后1 ~ 3周疼痛缓解。术后随访3个月,27例患者均生存。27例患者中淋巴结完全缓解12例,部分缓解8例,稳定4例,进展3例,总有效率74.1%(20//27)。本组术中及术后未发现剧烈疼痛、大出血、感染、骨髓抑制等严重并发症。结论 CT导向下组织间植入放射性125Ⅰ 粒子是治疗腹部转移性淋巴结具有近期疗效好、创伤小、并发症少等优点。

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备注/Memo

备注/Memo:
(收稿日期:2011-04-09)
国家自然科学基金资助项目(30970801)
更新日期/Last Update: