[1]谭华桥,李明华,朱悦琦,等.新型实验性颈内动脉虹吸段模型的建立[J].介入放射学杂志,2008,(01):44.
 TAN Huaqiao,LI Minghua,ZHU Yueqi,et al.Surgical construction of a novel simulated carotid siphon in canines[J].journal interventional radiology,2008,(01):44.
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新型实验性颈内动脉虹吸段模型的建立()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年01期
页码:
44
栏目:
实验研究
出版日期:
2008-01-15

文章信息/Info

Title:
Surgical construction of a novel simulated carotid siphon in canines
作者:
谭华桥李明华朱悦琦
200233上海交通大学附属第六人民医院放射科
Author(s):
TAN Hua-qiaoLI Ming-huaZHU Yue-qi FANG ChunWANG JueWU Chun-genCHENG Ying-shengXIE JianZHANG He
Sixth People's Hospital,Shanghai Jiaotong University,Shanghai200233,China
关键词:
血管内治疗颈内动脉颈总动脉动物模型
分类号:
R743.32
文献标志码:
B
摘要:
目的建立用于测试颅内支架性能的颈内动脉虹吸段动物模型。方法使用快速原型及脱蜡技术建立6只颈内动脉虹吸段约束装置。手术暴露并游离6只犬双侧颈总动脉。左侧颈总动脉近端暂时性夹闭,远端结扎并沿结扎点近侧切断。右侧颈总动脉远端暂时性夹闭,近端结扎并沿结扎点远侧切断。左侧颈总动脉近侧段穿过塑型装置,并与右侧颈总动脉远侧游离段端端吻合。术后1、2周、1个月血管造影,视觉评估虹吸段模型形态,血管通畅,吻合口狭窄及附壁血栓形成情况。结果所有实验犬均能耐受手术,无一只死亡或出现神经功能障碍。建模平均手术时间90min。术后1、2周、1个月血管造影,显示虹吸段模型空间结构与其人体原形高度相似,2例发生吻合口狭窄,1例吻合口附壁血栓形成。所有模型虹吸段随访中均保持通畅。结论采用体外约束装置,手术建立虹吸段模型切实可行,该模型具有高度可重复性、可靠性,可用于测试神经血管内材料。

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备注/Memo

备注/Memo:
收稿日期:2007-05-18
基金项目:国家自然科学基金(编号:30570540)
更新日期/Last Update: 2008-01-15