[1]朱智能,高小玲,黄遂斌,等.髂内动脉化疗栓塞联合双极等离子电切术治疗大体积膀胱癌的临床应用[J].介入放射学杂志,2020,29(06):572-576.
 ZHU Zhineng,GAO Xiaoling,HUANG Suibin,et al.The clinical effect of internal ilium artery chemoembolization combined with bipolar transurethral resection in saline for large- sized bladder cancer[J].journal interventional radiology,2020,29(06):572-576.
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髂内动脉化疗栓塞联合双极等离子电切术治疗大体积膀胱癌的临床应用()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
29
期数:
2020年06
页码:
572-576
栏目:
肿瘤介入
出版日期:
2020-06-25

文章信息/Info

Title:
The clinical effect of internal ilium artery chemoembolization combined with bipolar transurethral resection in saline for large- sized bladder cancer
作者:
朱智能 高小玲 黄遂斌 袁敬东 章传华
Author(s):
ZHU Zhineng GAO Xiaoling HUANG Suibin YUAN Jingdong ZHANG Chuanhua.
Department of Urinary Surgery, Wuhan Municipal No.1 Hospital, Wuhan, Hubei Province 430022, China
关键词:
【关键词】 膀胱尿路上皮癌 髂内动脉化疗栓塞 双极等离子电切 大体积肿瘤。
文献标志码:
A
摘要:
【摘要】 目的 探讨髂内动脉化疗栓塞(TACE)联合经尿道双极等离子电切术(TURis)治疗直径≥ 3 cm高危肌层浸润性膀胱癌的临床疗效。方法 选取不能或不愿接受膀胱全切手术的直径≥3 cm肌层浸润性膀胱癌患者58例为研究对象,采用抽签法随机分为对照组(A组)28例和观察组(B组)30例,A组单纯行传统术式经尿道膀胱肿瘤双极等离子电切术(TURis)治疗,B组采用经皮穿刺股动脉插管,实施髂内动脉TACE后2~3 d行TURis治疗,比较A组和B组的经尿道电切手术时间、术中出血量、导尿管保留时间、术后住院时间及术后3个月肿瘤复发率、术后2年肿瘤复发率、术后2年肿瘤特异生存率。
结果 B组30例患者均成功行TACE 治疗,介入手术成功率100%。两组电切手术均顺利完成,无中转开放术式。58例患者均获得随访,平均随访25(10~38)个月。B组手术时间(45.8±7.5) min、导尿管留置时间(2.7±1.2) d、术后住院时间(3.5±1.4) d,分别短于A组手术时间(56.3±11.7) min、导尿管留置时间(3.8±1.5) d、术后住院时间(4.9±1.6) d;B组出血量为(55.4±8.2) mL 低于A组(67.6±13.5) mL(P<0.05),差异均有统计学意义。B组术后3个月肿瘤复发率13.3%低于A组35.7%(P<0.05),B组术后2年肿瘤复发率53.3%明显低于A组78.6%(P<0.05),B组术后2年肿瘤特异生存率73.3%明显高于A组46.4%(P<0.05),差异有统计学意义。 结论 髂内动脉TACE联合TURis治疗直径≥3 cm的高危膀胱癌安全有效,明显减少术中出血,有利于肿瘤彻底切除,提高了保留膀胱功能患者的生活质量和肿瘤特异生存率。

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备注/Memo

备注/Memo:
(收稿日期:2019- 09- 03)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2020-06-16