[1]王亮,陆清声,冯睿,等.DeBakeyⅢ型主动脉夹层血流动力学数值模拟分析初步研究[J].介入放射学杂志,2010,(09):683.
 WANG Liang,LU Qingsheng,FENG Rui,et al.The preliminary hemodynamic study of DeBakeyⅢaortic dissection with patient-specific geometries[J].journal interventional radiology,2010,(09):683.
点击复制

DeBakeyⅢ型主动脉夹层血流动力学数值模拟分析初步研究()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年09期
页码:
683
栏目:
血管介入
出版日期:
2010-09-15

文章信息/Info

Title:
The preliminary hemodynamic study of DeBakeyⅢaortic dissection with patient-specific geometries
作者:
王亮陆清声冯睿王晨廖明芳景在平
200433上海第二军医大学长海医院血管外科(王亮、陆清声、冯睿、廖明芳、景在平);北京理工大学机电工程学院(王晨)
Author(s):
WANG LiangLU Qing-shengFENG Rui WANG ChenLIAO Ming-fangJING Zai-ping.
Department of Vascular Surgery,Changhai Hospital,the Second Military Medical University,Shanghai200433,China Corresponding author:JING Zai-ping,E-mail:nx.vascular@gmail.Com
关键词:
主动脉主动脉夹层计算流体力学血液动力学腔内隔绝术
分类号:
R543.16
文献标志码:
A
摘要:
目的探索血流动力学因素在DeBakeyⅢ型主动脉夹层发生、发展以及临床预后评估中的作用。方法通过CT扫描获取临床常见典型形态的DeBakeyⅢ型主动脉夹层断层图像序列,重建出三维主动脉夹层血流动力学分析计算机模拟模型,采用计算流体力学数值模拟方法对主动脉夹层真假腔内的血液流场进行数值模拟分析。结果①单破口型夹层假腔压强持续高于真腔压强,呈现“吹气球”效应;②当DeBakeyⅢ型主动脉夹层真腔受压狭窄时,真腔内压强将低于假腔内压强,夹层真腔内血流流线也会出现部分中断;③夹层撕破口附近的动脉管壁局部血流动力学因素可出现失衡现象。结论DeBakeyⅢ型主动脉夹层真假腔压强失衡可导致假腔持续扩张、压迫真腔。夹层管壁局部血流动力学改变可能是慢性期B型夹层破裂的危险因素。

参考文献/References:

[1]Auer J,Berent R,Eber B.Aortic dissection:incidence,natural history and impact of surgery[J].J Clin Basic Cardiol,2000,3:151-154.表3DeBakeyⅢ型主动脉夹层局部管腔壁面间压强差值(mmHg )
[2]Elefteriades JA.Natural history of thoracic aortic aneurysms :indications for surgery,and surgical versus nonsurgical risks[J].Ann Thorac Surg,2002,74:S1877-1880.
[3]Rutherford RB.Vascular Surgery[M],6th ed.Philadel-phia,ELSVIER SAUNDERS,Inc,2005:1512-1533.
[4]Raghavan ML ,Vorp DA,Federle MP ,et al.Wall stress distribution on three-dimensionally reconstructed models of human abdominal aortic aneurysm[J].J Vasc Surg,2000,31:760-769.
[5]Li Z,Kleinstreuer C.Blood flow and structure interactions in a stented abdominal aortic aneurysm model[J].Med Eng Phy,2005,27:369-382.
[6]Howell BA,Kim T,Cheer A,et al.Computational fluid dynamics within bifurcated abdominal aortic stent-grafts[J].J Endovasc Ther,2007,14:138-143.
[7]Fung GS,Lam SK,Cheng SW,et al.On stent-graft models in thoracic aortic endovascular repair:a computational investigation of the hemodynamic factors[J].Comput Biol Med,2008,38:484-489.
[8]Fung YC.Biomechanics Circulation[M].2nd Edition,Springer,New York,1997:108-205.
[9]Pedley TJ.The Fluid Mechanics of Large Blood Vessels[M].Cambridge University Press,Cambridge,1980:160-234.
[10]Shahcheraghi N,Dwyer HA,Cheer AY,et al.Unsteady and three-dimensional simulation of blood flow in the human aortic arch[J].J Biomech Eng,2002,124:378-387.
[11]Sueyoshi E,Sakamoto I,Hayashi K,et al.Growth rate of aortic diameter in patients with type B aortic dissection during the chronic phase[J].Circulation,2004;110:I1256-1261.
[12]Hiratzka LF,Bakriks GL,Beckman JA,et al.Guidelines for the diagnosis and management of patients with Thoracic Aortic diseases[J].Circulation,2010,published online Mar16,DOI :10.1161/CIR.0b013e3181d4739e.
[13]Lawford PV,Ventikos Y,Khir AW,et al.Modeling the interaction of hemodynamics and the artery wall:current status and future prospects[J].Biomed Pharmacother2008,62:530-535.

相似文献/References:

[1]赵珺 景在平 赵志青 包俊敏 冯翔 曲乐丰 陆清声.腹主动脉复合动脉瘤的腔内隔绝术治疗[J].介入放射学杂志,2003,(01):31.
[2]夏金国,施海彬,杨正强,等.Stanford B型主动脉夹层多型支架介入治疗的临床体会[J].介入放射学杂志,2010,(05):369.
 XIA Jinguo,SHI Haibin,YANG Zhengqiang,et al.Endovascular repair of Stanford B type aortic dissection by using different kinds of stents:clinical experience[J].journal interventional radiology,2010,(09):369.
[3]翟水亭,王国权,李天晓,等.Standford B型主动脉夹层覆膜支架腔内修复术围手术期并发症分析[J].介入放射学杂志,2010,(09):689.
 ZHAI Shuiting,WANG Guoquan,LI Tianxiao,et al.Transluminal stent-graft placement for Standford type B aortic dissections :an analysis of perioperative complications[J].journal interventional radiology,2010,(09):689.
[4]王 亮,冯 睿,陆清声,等.采用CT断层扫描图像构建DeBakey Ⅲ型主动脉夹层三维血流动力学数值模拟分析模型[J].介入放射学杂志,2010,(10):767.
 WANG Liang,FENG Rui,LU Qing-sheng,et al.The construction of realistic 3D hemodynamic models of DeBakey Ⅲ aortic dissection by using CT images and its application in computational mimic analysis[J].journal interventional radiology,2010,(09):767.
[5]滕皋军,邓钢,何仕诚,等.覆膜支架治疗降胸主动脉瘤[J].介入放射学杂志,2006,(03):137.
 TENG Gao-jun,DENG Gang,HE Shi-cheng,et al.Endoluminal stem-graft management for type Baortic dissection and descending thoracic aortic aneurysm[J].journal interventional radiology,2006,(09):137.
[6]肖亮,徐克,邵海波,等.主动脉半周覆膜支架生物相容性及封堵效果的实验研究[J].介入放射学杂志,2010,(11):883.
 XIAO Liang,XU Ke,SHAO Hai-bo,et al.Biocompatibility and occlusive efficiency of self-made aortic half-cycle stent-graft: an experimental study in dogs[J].journal interventional radiology,2010,(09):883.
[7]黄连军,蒋世良,赵世华,等.JOSTENT支架在治疗主动脉及外周动脉狭窄疾患中的应用[J].介入放射学杂志,2000,(02):73.
[8]姜海滨,黄新苗,白 元,等.经导管镍钛合金自膨式主动脉人工瓣膜支架植入的实验研究[J].介入放射学杂志,2011,(08):631.
 JIANG Hai-bin,HUANG Xin-miao,BAI Yuan,et al.Transcatheter aortic valve implantation with self-expandable nitinol valved stent: an experimental study in sheep[J].journal interventional radiology,2011,(09):631.
[9]黄文诺,王立富,王书祥,等.三维DSA在主动脉夹层腔内隔绝术中的应用[J].介入放射学杂志,2011,(06):487.
 HUANG Wen-nuo,WANG Li-fu,WANG Shu-xiang,et al.Clinical application of rotational three-dimensional digital subtraction angiography in performing endovascular isolation therapy for thoracic aortic dissection[J].journal interventional radiology,2011,(09):487.
[10]冯 睿,景在平,赵志青,等.主动脉弓上病变的双烟囱法腔内隔绝术[J].介入放射学杂志,2011,(07):510.
 FENG Rui,JING Zai-ping,ZHAO Zhi-qing,et al.Endovascular exclusion with double-chimney technology for treating aortic arch pathologies[J].journal interventional radiology,2011,(09):510.

备注/Memo

备注/Memo:
收稿日期:2010-06-18
基金项目:国家自然科学基金项目(30772140)
更新日期/Last Update: 2010-09-15