[1]李先浪,先正元,石荣书,等.原发性肝癌DSA表现特点与癌组织血管内皮细胞生长因子表达相关性研究[J].介入放射学杂志,2010,(05):377.
 LI Xianlang,XIAN Zhengyuan,SHI Rongshu,et al.The DSA characteristics and the expression of VEGF of primary hepatocellular carcinoma :a correlative study[J].journal interventional radiology,2010,(05):377.
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原发性肝癌DSA表现特点与癌组织血管内皮细胞生长因子表达相关性研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年05期
页码:
377
栏目:
肿瘤介入
出版日期:
2010-05-15

文章信息/Info

Title:
The DSA characteristics and the expression of VEGF of primary hepatocellular carcinoma :a correlative study
作者:
李先浪先正元石荣书
311300浙江省临安市人民医院放射科(李先浪、杜纯忠);遵义医学院附属医院影像科(先正元、石荣书、蒋国军)
Author(s):
LI Xian-langXIAN Zheng-yuanSHI Rong-shuJIANG Gu-junDu Chun-zhong
Lin’an Municipal People’s Hospital,Zhejiang Province311300,China
关键词:
肝癌数字减影血管造影血管内皮细胞生长因子表达相关性
分类号:
R735.7
摘要:
目的探讨肝细胞性肝癌(HCC)DSA表现特点与癌组织血管内皮生长因子(VEGF)表达的关系。方法选择54例经病理证实原发性HCC患者,根据其在DSA的表现特点,如肿瘤大小及多少、病灶边缘是否清晰、肿瘤血供情况(包括肿瘤血管的丰富度及是否有动静脉瘘等)等特点进行分析;用Elivision TMplus法对HCC组织切片进行VEGF定性检测,根据染色程度及阳性细胞的百分比进行综合分析;同时进行HE染色,用Edmmond法进行病理分级,本组把Ⅰ、Ⅱ级划为高分化组,Ⅲ、Ⅳ级划为低分化组。对结果进行统计学分析,采用SPSS13.0统计软件进行数据处理。结果肝癌组织的VEGF表达与癌组织血供特点、病灶数目多少、轮廓完整性及肿瘤分化程度相关(P<0.05或P<0.0167),与瘤体大小无关(P>0.05)。结论原发性肝癌DSA某些表现特征与肝癌组织的VEGF含量有一定相关性,通过观测DSA图像特征能提高对肝癌侵袭和转移评估的能力,给临床个性化治疗和判断预后提供参考。

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备注/Memo

备注/Memo:
收稿日期:2009-10-09
更新日期/Last Update: 2010-05-15