[1]叶开创,彭智猷,吴小雨,等.药物涂层球囊血管成形术治疗孤立性腘动脉慢性闭塞的近期效果[J].介入放射学杂志,2021,30(09):874-879.
　YE Kaichuang,PENG Zhiyou,WU Xiaoyu,et al.Short-term outcomes of drug-coated balloon angioplasty for isolated chronic occlusion of popliteal artery[J].journal interventional radiology,2021,30(09):874-879.
点击复制

药物涂层球囊血管成形术治疗孤立性腘动脉慢性闭塞的近期效果()

PDF下载中关闭

分享到：

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
30
期数:
2021年09
页码:
874-879
栏目:
血管介入
出版日期:
2021-09-25

文章信息/Info

Title:
Short-term outcomes of drug-coated balloon angioplasty for isolated chronic occlusion of popliteal artery
作者:
叶开创;  彭智猷;  吴小雨;  张 省;  王 新;  陆信武
Author(s):
YE Kaichuang;  PENG Zhiyou;  WU Xiaoyu;  ZHANG Xing;  WANG Xin;  LU Xinwu.
Department of Vascular Surgery， Affiliated Shanghai Ninth People’s Hospital， School of Medicine， Shanghai Jiao Tong University； Vascular Center of Shanghai Jiao Tong University， Shanghai 200011， China
关键词:
【关键词】 腘动脉闭塞性病变;  药物涂层球囊;  血管腔内治疗
文献标志码:
A
摘要:
【摘要】 目的 评价药物涂层球囊（DCB）血管成形术治疗孤立性腘动脉闭塞性病变的近期临床效果。 方法 回顾性分析2018年1月至2019年6月期间经DCB成形术治疗的孤立性腘动脉慢性闭塞性病变患者临床资料。主要研究终点为靶病变1年初期通畅率，次要研究终点1年二期通畅率、保肢率和临床症状改善等。 结果 共入组31例患者36条患肢（左侧19条），其中男20例；平均年龄72.7岁。14例患者16条患肢表现为重症肢体缺血（Rutherford分级4～6级）。手术技术成功率为83.3%（30/36）。6例患者靶病变需植入补救性支架，支架辅助技术均获成功。无患者发生远端动脉栓塞和腘动脉损伤，无死亡。平均随访7.8个月，有7例腘动脉再闭塞，其中3例系补救性支架植入患者，补救性支架再闭塞率为3/6。术后1年靶病变初期通畅率、二期通畅率分别为73.2%、83.6%，保肢率为86.1%，截肢/趾均发生于Rutherford分级6级患者。患肢平均踝-肱指数（ABI）由术前0.43上升至术后0.76，所有患者临床症状明显缓解。结论 DCB成形术治疗孤立性腘动脉慢性闭塞性病变安全，近期效果满意。补救性支架似并不能显著提高靶病变通畅率。

参考文献/References:

［1］ Mohapatra A， Saadeddin Z， Bertges DJ， et al. Nationwide trends in drug- coated balloon and drug- eluting stent utilization in the femoropopliteal arteries［J］. J Vasc Surg， 2020， 71： 560- 566.
［2］ Long CA， Zepel L， Greiner MA， et al. Use and 1- year outcomes with conventional and drug- coated balloon angioplasty in patients with lower extremity peripheral artery disease［J］. Am Heart J， 2019， 217：42- 51.
［3］ Kroger K， Santosa F， Goyen M. Biomechanical incompatibility of popliteal stent placement［J］. J Endovasc Ther， 2004， 11：686- 694.
［4］ Semaan E， Hamburg N， Nasr W， et al. Endovascular management of the popliteal artery： comparison of atherectomy and angioplasty［J］. Vasc Endovascular Surg， 2010， 44：25- 31.
［5］ Rastan A， Krankenberg H， Baumgartner I， et al. Stent placement versus balloon angioplasty for the treatment of obstructive lesions of the popliteal artery：a prospective， multicenter， randomized trial［J］. Circulation， 2013， 127：2535- 2541.
［6］ Scheinert D， Werner M， Scheinert S， et al. Treatment of Complex Atherosclerotic Popliteal Artery Disease With a New Self- Expanding Interwoven Nitinol Stent［J］. JACC Cardiovasc Interv， 2013， 6：65- 71.
［7］ Semaan E， Hamburg N， Nasr W， et al. Endovascular management of the popliteal artery： comparison of atherectomy and angio- plasty［J］. Vasc Endovascular Surg， 2010， 44： 25- 31.
［8］ Gokgol C， Diehm N， Kara L， et al. Quantification of popliteal artery deformation during leg flexion in subjects with peripheral artery disease： a pilot study［J］. J Endovasc Ther， 2013， 20：828- 835.
［9］ Chang IS， Chee HK， Park SW， et al. The primary patency and fracture rates of self- expandable nitinol stents placed in the popliteal arteries， especially in the P2 and P3 segments， in Korean patients［J］. Korean J Radiol， 2011， 12：203- 209.
［10］ Goltz JP， Ritter CO， Kellersmann R， et al. Endovascular treatment of popliteal artery segments P1 and P2 in patients with critical limb ischemia： initial experience using a helical nitinol stent with increased radial force［J］. J Endovasc Ther， 2012， 19：450- 456.
［11］ Rastan A， Krankenberg H， Baumgartner I， et al. Stent placement vs. balloon angioplasty for popliteal artery treatment： two- year results of a prospective，multicenter，randomized trial［J］. J Endovasc Ther， 2015， 22： 22- 27.
［12］ Tosaka A， Soga Y， Iida O， et al. Classification and clinical impact of restenosis after femoropopliteal stenting［J］. J Am Coll Cardiol， 2012， 59： 16- 23.
［13］ Parthipun A， Diamantopoulos A， Kitrou P， et al. Use of a new hybrid heparin- bonded nitinol ring stent in the popliteal artery： procedural and mid- term clinical and anatomical outcomes［J］. Cardiovasc Intervent Radiol， 2015， 38：846- 854.
［14］ 蔡志文， 谷涌泉. 定向斑块旋切联合药物涂层球囊治疗股腘动脉病变进展［J］. 介入放射学杂志， 2019， 28：301- 304.
［15］ Rastan A， McKinsey J， Garcia LA， et al. One- year outcomes following directional atherectomy of popliteal artery lesions： subgroup analysis of the prospective， multicenter DEFINITIVE LE trial［J］. J Endovasc Ther， 2018， 25： 100- 108.
［16］ Stavroulakis K， Schwindt A， Torsello G， et al. Directional atherectomy with antirestenotic therapy vs drug- coated balloon angioplasty alone for isolated popliteal artery lesions［J］. J Endovasc Ther， 2017， 24： 181- 188.
［17］ Tepe G， Micari A， Keirse K， et al. Drug- coated balloon treatment for femoropopliteal artery disease: the chronic total occlusion cohort in the IN.PACT global study［J］. J Am Coll Cardiol Intv， 2019， 12：484- 493.
［18］ Baumhakel M， Chkhetia S， Kindermann M. Treatment of femoro- popliteal lesions with scoring and drug- coated balloon angioplasty： 12- month results of the DCB- Trak registry［J］. Diagn Interv Radiol， 2018， 24：153- 157.
［19］ Kijima Y， Yoshinaka H， Hirata M， et al. Impaired wound healing and expansion of a large ulcer after bevacizumab with paclitaxel for skin metastases from breast cancer： report of a case［J］. Surg Today， 2015， 45：498- 502.

相似文献/References:

[1]解旭品,方 欣,黄昌拼,等.紫杉醇药物涂层球囊治疗股腘动脉支架内再狭窄18例 [J].介入放射学杂志,2017,(06):544.
　XIE Xupin,FANG Xin,HUANG Changpin,et al.Drug- coated balloon with paclitaxel for in- stent restenosis of femoral popliteal artery： initial experience in 18 patients[J].journal interventional radiology,2017,(09):544.
[2]蔡志文,谷涌泉.定向斑块旋切联合药物涂层球囊治疗股腘动脉病变进展 [J].介入放射学杂志,2019,28(03):301.
　CAI Zhiwen,GU Yongquan..Directional atherectomy combined with drug- coated balloon dilatation for femoropopliteal artery diseases： recent advances in research[J].journal interventional radiology,2019,28(09):301.
[3]焦玉浩,郭建明,齐立行,等.药物涂层球囊治疗肾动脉支架内再狭窄4例[J].介入放射学杂志,2019,28(08):782.
　JIAO Yuhao,GUO Jianming,QI Lihang,et al.Drug- coated balloon therapy for renal artery in- stent restenosis： preliminary results in four patients[J].journal interventional radiology,2019,28(09):782.
[4]谷涌泉,张成超.血管减容联合药物涂层球囊在下肢动脉硬化闭塞病变治疗中的应用[J].介入放射学杂志,2020,29(06):636.
　GU Yongquan,ZHANG Chengchao..Application of vascular volume reduction combined with drug- coated balloon dilation for arteriosclerosis obliterans disease of lower extremities[J].journal interventional radiology,2020,29(09):636.
[5]王鹏,陈晓伟,包 晗,等.药物涂层球囊与金属裸支架治疗下肢动脉硬化闭塞症效果和安全性对比[J].介入放射学杂志,2019,28(12):1176.
　WANG Peng,CHEN Xiaowei,BAO Han,et al.Drug- coated balloon versus bare metal stent for the treatment of atherosclerotic occlusion of lower extremities： comparison of clinical efficacy and safety[J].journal interventional radiology,2019,28(09):1176.
[6]吴 斐,曾 倩,崔文军,等.药物涂层球囊联合斑块旋切术治疗股浅动脉支架内再闭塞 [J].介入放射学杂志,2021,30(05):508.
　WU Fei,ZENG Qian,CUI Wenjun,et al.Drug-coated balloon angioplasty combined with directional atherectomy for the treatment of superficial femoral artery in-stent re-occlusion[J].journal interventional radiology,2021,30(09):508.
[7]潘 涛,田诗云,张 涛,等.贫血对股腘动脉硬化闭塞症患者药物涂层球囊治疗后再狭窄的影响[J].介入放射学杂志,2021,30(08):799.
　PAN Tao,TIAN Shiyun,ZHANG Tao,et al.The effect of anemia on restenosis in patients with femoropopliteal atherosclerotic occlusion after drug-coated balloon angioplasty[J].journal interventional radiology,2021,30(09):799.
[8]王 翔,郭建明,崔世军,等.TAPAS血管内封闭导管紫杉醇浸润与紫杉醇药物涂层球囊治疗股腘动脉狭窄的对比[J].介入放射学杂志,2023,32(06):542.
　WANG Xiang,GUO Jianming,CUI Shijun,et al.Paclitaxel infiltration using TAPAS intravascular closed catheter versus paclitaxel drug-coated balloon for the treatment of femoropopliteal artery stenosis： a comparison study[J].journal interventional radiology,2023,32(09):542.
[9]王佳旺,吴 琼,刘莲莲,等.光学相干层析成像指导药物球囊处理极晚期冠状动脉支架事件1例[J].介入放射学杂志,2023,32(10):1052.
　WANG Jiawang,WU Qiong,LIU Lianlian,et al.Optical coherence tomography imaging- guided drug balloon treatment for the extremely- advanced coronary stent event： report of one case[J].journal interventional radiology,2023,32(09):1052.

备注/Memo

备注/Memo:
（收稿日期：2020- 02- 08）
（本文编辑：边 佶）
更新日期/Last Update: 2021-09-13