[1]金 灿,罗 俊,武英彪,等.心房颤动伴慢性肾脏病患者经皮左心耳封堵术后抗栓治疗方案研究[J].介入放射学杂志,2020,29(12):1187-1190.
　JIN Can,LUO Jun,WU Yingbiao,et al.Antithrombotic therapeutic regimens for atrial fibrillation patients with chronic kidney disease after receiving left atrial appendage closure： a clinical study[J].journal interventional radiology,2020,29(12):1187-1190.
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心房颤动伴慢性肾脏病患者经皮左心耳封堵术后抗栓治疗方案研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
29
期数:
2020年12
页码:
1187-1190
栏目:
心脏介入
出版日期:
2020-12-25

文章信息/Info

Title:
Antithrombotic therapeutic regimens for atrial fibrillation patients with chronic kidney disease after receiving left atrial appendage closure： a clinical study
作者:
金 灿;  罗 俊;  武英彪;  朱 茜;  方 明;  王赛华;  丛欣鹏;  王雪君;  王温慧;  宁忠平
Author(s):
JIN Can;  LUO Jun;  WU Yingbiao;  ZHU Qian;  FANG Ming;  WANG Saihua;  CONG Xinpeng;  WANG Xuejun;  WANG Wenhui;  NING Zhongping.
Department of Cardiology， Affiliated Zhoupu Hospital of Shanghai University of Medicine and Health Sciences， Shanghai 201318， China
关键词:
【关键词】 心房颤动;  左心耳封堵术;  慢性肾脏病;  抗血栓治疗
文献标志码:
A
摘要:
【摘要】 目的 探讨非瓣膜性心房颤动（房颤）伴慢性肾脏病（CKD）患者经皮左心耳封堵术（LAAC）后最佳抗栓治疗方案。 方法 对2018年1月至2019年2月于上海周浦医院接受LAAC治疗的68例非瓣膜性房颤伴CKD患者进行单中心回顾性分析。其中，38例LAAC术后服用华法林至少45 d（A组），30例术后服用双联抗血小板治疗6个月（B组）。观察两组患者围术期以及术后3、6、12 个月随访期装置相关血栓（DRT）、血栓栓塞事件和大出血事件发生率。 结果 两组患者年龄、性别、永久性房颤、伴高血压、伴糖尿病、伴冠心病、伴心力衰竭、脑卒中史、CHA2DS2-VASc评分、HAS-BLED评分等基线资料差异均无统计学意义（P＞0.05）。两组患者LAAC术均获成功。两组患者围手术期7 d内心脏压塞、血栓栓塞及大出血事件发生率差异均无统计学意义（P＞0.05）；术后45～60 d DRT、血栓栓塞、大出血事件及死亡发生率差异均无统计学意义（P＞0.05）；术后1年血栓栓塞、大出血事件及死亡发生率差异均无统计学意义（P＞0.05）。 结论 房颤伴CKD患者经皮LAAC术后双联抗血小板治疗，不增加近期DRT、血栓栓塞及大出血事件风险。

参考文献/References:

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备注/Memo

备注/Memo:
（收稿日期：2020- 03- 22）
（本文编辑：边 佶）
更新日期/Last Update: 2020-12-16